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. 2021 Jan 1;11(5):2247–2262. doi: 10.7150/thno.51666

Figure 5.

Figure 5

Activation of NMDAR reduces insulin sensitivity in mice fed with a normal chow diet. (A) C57BL/6 mice received intraperitoneal injections of NMDA from month 1 to month 6 and were fed with a normal chow diet. (B) Measurement of fasting blood glucose of mice treated with NMDA for 3 months or 6 months (n = 10). (C-E) Measurement of blood glucose during IGTT of mice treated with NMDA for 3 months or 6 months (n = 8). (F-H) Measurement of blood glucose during the IITT of mice treated with NMDA for 3 months or 6 months (n = 8). * vs Control, **P < 0.01; ***P <0.001. All data are presented as the mean ± SEM.