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. 2021 Jan 1;11(5):2108–2122. doi: 10.7150/thno.48112

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STK39 promotes migration, invasion and EMT in HCC cells. (A) Knockdown or overexpression of STK39 in HCC cells, invasive or migrated cells were measured by transwell assay with or without matrix. (B) Knockdown of STK39 in HuH7 cells by siRNA, cell migration ability was evaluated by wound healing assay. (C) Stable knockdown of STK39 in HCCLM3 cells by shRNA, cell migration ability was evaluated by wound healing assay. (D) Knockdown of STK39 in HuH7 cells by siRNA, expression of STK39, CDH1 and VIM were assessed by immunoblotting. (E) Overexpressing STK39 in HuH7 cells, expression of STK39, CDH1 and VIM were assessed by immunoblotting. Data are shown as mean ±SEM. *p<0.05; ***p<0.001.