Table 1.
Clinical characteristics of the PD-L1 expression dataset
| Characteristics | Total (n = 939) | Training cohort (n = 750) | Validation cohort (n = 93) | P Value* | Test cohort (n = 96) | P Value** |
|---|---|---|---|---|---|---|
| Age, year, mean ± SD | 58.8 ± 10.7 | 58.9 ± 10.7 | 58.0 ± 10.3 | 0.462 | 59.0 ± 11.3 | 0.892 |
| Gender, n (%) | 0.838 | 0.408 | ||||
| Male | 576 (61.3) | 455 (60.7) | 58 (62.4) | 63 (65.6) | ||
| Female | 363 (38.7) | 295 (39.3) | 35 (37.6) | 33 (34.4) | ||
| Smoking status, n (%) | 0.938 | 0.409 | ||||
| Never | 432 (46.0) | 348 (46.4) | 43 (46.2) | 41 (42.7) | ||
| Occasionally | 374 (39.8) | 300 (40.0) | 36 (38.7) | 38 (39.6) | ||
| Constantly | 95 (10.1) | 74 (9.7) | 11 (11.8) | 10 (10.4) | ||
| Unknown | 38 (4.0) | 28 (3.7) | 3 (3.2) | 7 (7.2) | ||
| Family history of cancer, n (%) | 0.686 | 0.437 | ||||
| No | 764 (81.4) | 610 (81.3) | 79 (84.9) | 75 (78.1) | ||
| Yes | 139 (14.8) | 113 (15.1) | 11 (11.8) | 15 (15.6) | ||
| Unknown | 36 (3.8) | 27 (3.6) | 3 (3.2) | 6 (6.3) | ||
| PD-L1 expression, n (%) | 0.988 | 0.995 | ||||
| ≥ 50% | 328 (34.9) | 261 (34.8) | 33 (35.5) | 34 (35.4) | ||
| < 50% | 611 (65.1) | 489 (65.2) | 60 (64.5) | 62 (64.6) |
Categorical data are shown as numbers (%) and continuous data as mean ± SD;
*The P value is the test result of the training cohort and the validation cohort;
**The P value is the test result of the training cohort and the test cohort.