Table 6.
Time course of cellular immune responses in study animals.
| AAV positive responses in test samples | ||||||
|---|---|---|---|---|---|---|
| Triplicate mean SFU/million PBMCs | Cut point ratio | |||||
| Donor | Sample collection day (post dose) | Mock (DMSO) | AAV5_pool 1 | AAV5_pool 2 | AAV5_pool 1/Mock | AAV5_pool 2/Mock |
| A | D13 | 3 | 12 | 7 | NA | NA |
| D28 | 52 | 75 | 77 | 1.45 | 1.48 | |
| B | D13 | 3 | 12 | 3 | NA | NA |
| D28 | 10 | 48 | 107 | 4.83 | 10.67 | |
Responses at or above the LOD (75 SFU/million PBMCs) are highlighted in bold. Response ratios for peptide response at or above the LOD are also shown.
NA not applicable.