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Fenofibrate inhibits Wnt signaling in very low–density lipoprotein receptor (Vldlr)−/− retinas. Levels of (A,B) p-glycogen synthase kinase 3 beta (GSK3β), (A,C) GSK3β, (D,E) non–p-β-catenin, and (D,F) β-catenin were determined by Western blot analysis and quantified by densitometry in eyecups of wild-type mice and Vldlr −/− mice fed with control chow (Vldlr −/− + vehicle) or fenofibrate chow (Vldlr −/− + feno) (mean ± SEM; n = 8. **p < 0.01 and ***p < 0.001).
