Table 1.
Injured Corneas (Time After Lesion) | |||||
---|---|---|---|---|---|
Mechanonociceptors | Intact Corneas | 3–8 h | 24–48 h | 72 h | 6–15 Days |
Spontaneous activity (imp/s) | 0.008 ± 0.004 (4/225) | 0.022 ± 0.022 (1/25) | 0 ± 0 (0/48) | 0 ± 0 (0/29) | 0 ± 0 (0/28) |
Mechanical threshold (mN) | 0.66 ± 0.005 | 0.50 ± 0.09 | 0.35 ± 0.02* | 0.60 ± 0.14 | 0.57 ± 0.11 |
n | 242 | 25 | 48 | 29 | 28 |
Data are mean ± SEM; n = number of recorded fibers; number in brackets indicate the number of fibers with spontaneous activity/number of recorded fibers. * P < 0.05, Mann–Whitney U test, compared with intact corneas.