Table III.
2-year PFS | 2-year OS | |||||
---|---|---|---|---|---|---|
Variables | RR | 95% CI | P-value | RR | 95% CI | P-value |
SUVmax | ||||||
<17.6 | 1 | 1 | ||||
≥17.6 | 1.575 | 0.673–3.690 | 0.295 | 1.531 | 0.591–3.969 | 0.381 |
SUVmean | ||||||
<10.6 | 1 | 1 | ||||
≥10.6 | 1.208 | 0.522–2.798 | 0.659 | 1.531 | 0.591–3.969 | 0.381 |
MTVmax (cm3) | ||||||
<63.5 | 1 | 1 | ||||
≥63.5 | 4.716 | 1.722–12.916 | 0.003a | 6.683 | 1.924–23.209 | 0.003a |
MTVsum (cm3) | ||||||
<132.6 | 1 | 1 | ||||
≥132.6 | 2.267 | 0.946–5.434 | 0.067 | 3.564 | 1.265–10.043 | 0.016a |
TLGmax (g) | ||||||
<628.7 | 1 | 1 | ||||
≥628.7 | 4.716 | 1.722–12.916 | 0.003a | 6.433 | 1.852–22.350 | 0.003a |
TLGsum (g) | ||||||
<1135.9 | 1 | 1 | ||||
≥1135.9 | 2.076 | 0.868–4.968 | 0.101 | 3.267 | 1.159–9.211 | 0.025a |
Dmax (cm) | ||||||
<5.7 | 1 | 1 | ||||
≥5.7 | 4.716 | 1.722–12.916 | 0.003a | 6.895 | 1.982–23.984 | 0.002a |
Interim treatment response | ||||||
CR | 1 | 1 | ||||
Non-CR | 4.642 | 1.699–11.685 | 0.003a | 6.496 | 1.855–21.176 | 0.002a |
Statistically significant. PFS, progression-free survival; OS, overall survival; RR, relative risk; CI, confidence interval; SUVmax, maximum standardized uptake value; SUVmean, mean standardized uptake value; MTVmax, metabolic tumor volume of the maximum lesion; MTVsum, sum of metabolic tumor volume; TLGmax, total lesion glycolysis of the maximum lesion; TLGsum, sum of total lesion glycolysis; Dmax, maximum diameter of the maximum lesion; CR, complete remission.