Figure 2.

Association between log-transformed Se-SMRP levels and malignant pleural mesothelioma RR estimated through the Cox regression analysis, adjusted for sex, age at diagnosis, disease stage, histological subtype and ECOG-PS, using a three-knot restricted cubic splines. Se-SMRP levels were log-transformed to decrease the influential effect of potential outlying data points. 95% confidence limits for RR are presented at the top of the figure. 95%-Low (RR) and 95%-Upp (RR), 95% lower and upper limits for RR. RR, mortality risk; Se-SMRP, serum soluble mesothelin-related protein.