Table 1.
Clinical Characteristics of Study Patients
| Factor | n=110 | |
|---|---|---|
| Age (year) | 70.1 ± 7.9 | |
| Gender (%) | Female | 20 (18.2) |
| Male | 90 (81.8) | |
| Diabetes mellitus (%) | 42 (38.2) | |
| Etiology (%) | HBV | 14 (12.7) |
| HCV | 63 (57.3) | |
| NBNC | 33 (30.0) | |
| Alcohol abuse (%) | 44 (40.0) | |
| Albumin (g/L) | 40 [35, 42] | |
| ALT (IU/L) | 38 [25, 56] | |
| AST (IU/L) | 43 [29, 64] | |
| Total bilirubin (µmol/L) | 11.9 [8.5, 15.3] | |
| Platelet count (x109/L) | 158 [121, 192] | |
| Prothrombin activity (%) | 91.6 [82.2, 101.2] | |
| ICGR15 (%) | 13.7 [9.4, 19.1] | |
| Child-Pugh (%) | A | 96 (87.3) |
| B | 14 (12.7) | |
| Tumor size (cm) | 5.61±3.75 | |
| Tumor number | 2 | 66 (60.0) |
| 3 | 20 (18.2) | |
| 4 | 10 (9.1) | |
| ≥5 | 14 (12.7) | |
| Tumor type (%) | Simple nodular | 55 (50.0) |
| Simple nodular + extra nodular | 31 (28.2) | |
| Confluent multinodular | 23 (20.9) | |
| Invasive | 1 ( 0.9) | |
| Tumor site (%) | Unilateral | 75 (68.2) |
| Bilateral | 35 (31.8) | |
| AFP (µg/L) | 35.3 [7.9, 416.4] | |
| PIVKA-II (mAU/mL) | 237 [47, 5058] | |
| Blood loss (ml) | 665 [311, 1423] | |
| Operation time (min) | 307 [232, 376] | |
| Operation method (%) | Anatomical | 43 (39.1) |
| Anatomical + partial | 18 (16.4) | |
| Partial | 49 (44.5) | |
| Combination of ablation (%) |
Resection only | 96 (87.3) |
| Resection + ablation | 14 (12.7) | |
| Intraoperative transfusion (%) | 38 (34.6) | |
| Complication (Clavien-Dindo, grade ) |
II | 14 (12.7) |
| IIIa | 27 (24.6) | |
| IIIb | 1 (0.9) | |
| IVa | 1 (0.9) | |
ALT, alanine aminotransferase; AST, aspartate aminotransferase; ICGR15, indocyanine green retention rate at 15 minutes; AFP, α-fetoprotein; PIVKA-II, protein induced by vitamin K absence or antagonist-II; HBV, hepatitis B virus; HCV, hepatitis C virus; NBNC, negative of hepatitis B and hepatitis C virus; Age and tumor size are expressed as mean ± SD. Other data are expressed as median with 25th and 75th percentiles.