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. 2021 Jan 10;21:22. doi: 10.1186/s12888-020-02981-7

Table 1.

Association between unemployment rate and substance abuse treatment admissions, 1993–2016

Primary diagnosis Model 1 Model 2 Model 3
β^ SE(β^) p-value β^ SE(β^) p-value β^ SE(β^) p-value
 Opiates 0.087 0.012 <.001 0.002 0.010 0.84 0.005 0.008 0.54
 Cocaine 0.081 0.014 <.001 0.033 0.011 <.01 −0.004 0.009 0.64
 Alcohol 0.050 0.011 <.001 0.039 0.007 <.001 0.026 0.007 <.001
 Marijuana/hashish 0.036 0.012 <.01 0.024 0.009 <.01 0.006 0.009 0.49
 Stimulants −0.081 0.016 <.001 −0.057 0.012 <.001 − 0.067 0.010 <.001
 Other drugs 0.095 0.013 <.001 0.068 0.011 <.001 0.049 0.010 <.001
Any diagnosis
 Opiates 0.080 0.014 <.001 0.009 0.010 0.34 0.010 0.008 0.22
 Cocaine 0.063 0.012 <.001 0.030 0.009 <.001 −0.002 0.008 0.80
 Alcohol 0.041 0.011 <.001 0.029 0.007 <.001 0.017 0.007 0.01
 Marijuana/hashish 0.029 0.011 <.01 0.025 0.008 <.01 0.010 0.007 0.16
 Stimulants −0.066 0.014 <.001 −0.033 0.010 <.01 −0.040 0.009 <.001
 Other drugs 0.098 0.014 <.001 0.065 0.011 <.001 0.050 0.010 <.001

p < 0.05 is presented in bold. Primary diagnosis represents primary substances cited for alcohol or drug treatment. Any diagnosis represents that the substance was one of the primary, secondary, or tertiary substances cited for alcohol or drug treatment

Model 1 adjusted all listed state-level characteristics, including log of population, mean age, percentage of state population that is male, percentage of state population that is white, state insurance coverage rate, state median household income (in thousands), medical marijuana laws, census division fixed effects and survey year. State beer taxes were adjusted for alcohol substance use treatment

Model 2 adjusted for state fixed effects to control unobserved confounding influences that are time-invariant and state-specific in addition to Model 1 state-level characteristics

Model 3 added interaction between state and year to Model 2, in order to allow for a state- unique time trend and control for unobserved state-level factors that evolve at a constant smooth function