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. Author manuscript; available in PMC: 2021 Jan 11.
Published in final edited form as: Trends Cell Biol. 2020 Feb 20;30(5):341–353. doi: 10.1016/j.tcb.2020.01.009

Figure 1 -. Differential lipid interactions drive lateral organization.

Figure 1 -

(A) Saturated lipids and cholesterol interact more favorably with each other than with unsaturated lipids. (B) Collectively, these differential interactions oppose the entropic tendency towards random mixing. When the various interactions sufficiently outweigh the demixing cost (dGdemixing ~ −kT), stable lateral domains are formed.