Table I. Serum analyses.
Serum pooled from six PITPα+/+ and PITPα−/− mice each, varying in age from P6 to P9, were subjected to a comprehensive mammalian chemistry panel performed by Antech Diagnostics (Farmingdale, NY). Values represent the averages of triplicate measurements obtained from three different sets of mice. Parameters that differ significantly between PITPα+/+ and PITPα−/− mice are highlighted at top of the table. The abbreviations used are: APase, alkaline phosphatase; AST, aspartate aminotransferase; CPK, creatinine phosphokinase; ALT, alanine aminotransferase.
Parameter | PITPα+/+ | PITPα−/− |
---|---|---|
Bilirubin | 0.84 ± 0.16 mg/dl | 1.54 ± 0.10 mg/dl |
APase | 809 ± 160 units/liter | 1497 ± 179 units/liter |
AST | 135 ± 9 units/liter | 250 ± 18 units/liter |
CPK | 4892 ± 42 units/liter | 6439 ± 147 units/liter |
Creatinine | 0.44 ± 0.08 mg/dl | 0.44 ± 0.08 mg/dl |
Total protein | 3.10 ± 0.34 g/dl | 3.10 ± 1.33 g/dl |
ALT | 52.4 ± 18.3 units/liter | 46.1 ± 13.2 units/liter |
Albumin | 1.70 ± 0.18 g/dl | 1.60 ± 0.17 g/dl |
Cholesterol | 134 ± 14 mg/dl | 137 ± 11 mg/dl |
Calcium | 7.04 ± 0.24 mg/dl | 8.28 ± 1.70 mg/dl |
Phosphorus | 11.4 ± 1.5 mg/dl | 11.3 ± 1.3 mg/dl |
Sodium | 115 ± 14 Meq/liter | 113 ± 8 Meq/liter |
Potassium | 7.2 ± 1.2 Meq/liter | 7.3 ± 0.9 Meq/liter |
Chloride | 50.6 ± 11.9 Meq/liter | 45.3 ± 3.0 Meq/liter |
Globulin | 1.20 ± 0.25 g/dl | 1.50 ± 32 g/dl |
Urea N2 | 22.0 ± 5.0 mg/dl | 25.0 ± 7.5 mg/dl |