Table 1.
Agreement Between RT-PCR and ID Now (95% CI) in Symptomatic and Asymptomatic Patients
| Site | Bed Size | Total Samples Tested | ID Now-/PCR+ | ID Now-/PCR- | ID Now+/No PCR | ID Now+/PCR- | ID Now Positive Rate, % | False Negative Rate | Negative Agreement (NPV) | Sensitivity | Performance Agreement (Fleiss Kappa) |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Symptomatic | |||||||||||
| 1 | 548 | 394 | 9 (6a–3b) | 352 (258a–94b) | 33 | 0 | 8.61 | 21.43 (10.30–36.81) | 97.51 (95.32–98.85) | 78.57 (63.19–89.70) | 0.855 (0.757–0.953) |
| 2 | 497 | 341 | 8 | 292 | 41 | 0 | 12.02 | 16.33 (7.32–29.66) | 97.33 (94.81–98.84) | 83.67 (70.34–92.68) | 0.898 (0.792–1.003) |
| 3 | 304 | 743 | 22 | 524 | 197 | 0 | 26.51 | 10.05 (6.40–14.81) | 95.97 (93.96–97.46) | 89.95 (85.19–93.60) | 0.927 (0.855–0.998) |
| 4 | 66 | 57 | 0 | 54 | 3 | 0 | 5.26 | 0.00 (0.00–70.76) | 100.00 (93.40–100.00) | 100.00 (29.24–100.00) | 1 (0.74–1.26) |
| 5 | 133 | 34 | 0 | 33 | 1 | 0 | 2.94 | 0.00 (0.00–97.50) | 100.00 (89.42–100.00) | 100.00 (2.50–100.00) | 1 (0.664–1.336) |
| Total | |||||||||||
| All | 1547 | 1569 | 39 | 1255 | 275 | 0 | 17.58 | 12.42 (8.98–16.59) | 96.99 (95.90–97.85) | 87.58 (83.41–91.02) | 0.917 (0.867–0.966) |
| Asymptomatic | |||||||||||
| 1 | 548 | 386 | 3 | 383 | 0 | 0 | 99.22 (97.75–99.84) |
Abbreviations: PCR, polymerase chain reaction; NPV, negative predictive value; RT-PCR, reverse transcription polymerase chain reaction.
aAbbott m2000.
bCepheid GeneXpert.