. 2020 Dec 29;2(1):iqaa007. doi: 10.1093/oxfimm/iqaa007

Table 1:

Summary of T cell subset perturbation in peripheral blood in COVID-19

Subset	Change in COVID-19 (as percentage of all T cells)	Higher proportions of this subset correlate with:	References
Naïve T cells	Decrease		[10]
Naïve CD4⁺ T cells		More severe disease	[12]
Activated T_fh	Increased	More severe disease	[13, 14]
Th17	Increased		[14]
Non-conventional (CCR6⁺CCR4⁺ CD161⁺IL-1RI⁺) Th1 (Th1^∗)	Increased		[14]
Tregs	Increased in some	More severe disease	[12, 14, 15]
Activated CD4 T_CM-like	Increased		[10]
CD4⁺ T_EMRA	Increased	Milder disease	[10, 16, 17]
T_CM		Milder disease	[16]
CD4⁺ memory cells		Milder disease	[12]
Th2		More severe disease	[8, 12]
CD8⁺ T_EMRA	Increased	Milder disease	[10, 16]
CD8⁺CD27⁻CCR7⁺ T_EM	Increased		[10]
CD8⁺CD27⁺CCR7⁻ T_EM	Decreased		[10]
CD4⁺CD8⁺ double‐positive T cells	Increased		[18]
MAIT	Decreased (in periphery)	Milder disease	[19, 20]