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. 2021 Jan 2;38(5):1966–1979. doi: 10.1093/molbev/msaa337

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© The Author(s) 2021. Published by Oxford University Press on behalf of the Society for Molecular Biology and Evolution.

This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0/), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is properly cited. For commercial re-use, please contact journals.permissions@oup.com

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Fig. 4. — Principal component analysis of chain. (A) Projection of the motion along the first eigenvector for the chain A of D614 (left) and G614 (right). The color code from green to blue and the thickness of the tube identify the amplitude of the motion. (B) Evolution of the distance calculated between the center of mass of the NTD and the RBD in D614 (black) and G614 (red) as a function of time. (C) Distance fluctuation matrices calculated for chain A in D614 (left) and G614 (right). The rectangles underline the regions with differences between the two proteins.