Table 1.
The interactions formed between GRP78 SBD domain and the new SARS-CoV-2 spike model based on docking with HADDOCK. Table represents the hydrogen bonds generated between the new SARS-CoV-2 spike model and host cell-surface GRP78 SBD during HADDOCK based docking.
| HYDROGEN BOND = 26 | ||
|---|---|---|
| Residue from New SARS-COV2 Spike | Residue from GRP-78 | Bond Length(Å) |
| SER 432 | GLY 430 | 3.17 |
| THR 433 | GLU 606 | 3.13 |
| ASN 479 | GLY 652 | 2.29 |
| ASN 479 | GLY 652 | 2.29 |
| ASN 479 | GLY 652 | 3.39 |
| ASN 479 | GLY 652 | 3.39 |
| TYR 484 | THR 428 | 3.37 |
| GLY 488 | TYR 466 | 3.13 |
| GLU 427 | THR 486 | 3.21 |
| GLU 427 | THR 486 | 3.21 |
| TYR 466 | THR 486 | 3.04 |
| GLN 609 | SER 432 | 3.43 |
| GLN 609 | SER 432 | 3.43 |
| TRP 476 | ASN 457 | 3 .25 |
| ASN 479 | THR 460 | 3.12 |
| ASN 479 | THR 460 | 3.12 |
| ASN 479 | THR 460 | 3.45 |
| ASN 479 | THR460 | 3.45 |
| THR 486 | GLU 427 | 2.59 |
| THR 486 | THR473 | 3.35 |
| TYR 491 | ASP 483 | 3.06 |
| ASN 479 | THR 460 | 3.12 |
| ASN 479 | THR 460 | 3.45 |
| THR 486 | THR 473 | 3.35 |
| TYR 491 | THR 481 | 2.89 |
| TYR 484 | THR 651 | 2.83 |