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. 2020 Dec 18:bbaa376. doi: 10.1093/bib/bbaa376

Figure 4.

Figure 4

Viral infection literature and drug prediction analysis validates SARS-CoV-2 infection responses and suggests relevant pathways for subsequent study. (A) A validation GEO viral literature screen was conducted of all publically available literature on viral infections. Analysis finds SARS-CoV-2 infection is most closely related to published studies of SARS and respiratory viral infections. (B) Predictive drug screening suggests molecules of interest targeting inflammatory, infection, lung fibrotic and coagulation factors may be of particular relevance to treating early-stage COVID-19 disease.