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. 2020 Nov 30;13(1):e12828. doi: 10.15252/emmm.202012828

Figure EV3. In vitro cytotoxicity and plasma stability and of ACE2‐Fc.

Figure EV3

  • A, B
    Two normal human bronchial epithelial cells were incubated with ACE2‐Fc and normal human IgG at the indicated concentrations for 72 h, and cell viability was analyzed by MTS assay. Error bars represent the standard deviation (SD), n = 2 in left; n = 3 in right. The dotted line represents the 50% of cell viability.
  • C
    In vitro serum stability of ACE2‐Fc. ACE2‐Fc was incubated with 50% normal human serum at 37°C for up to 10 days. At the indicated time points, samples were collected to quantify the binding ability of ACE2‐Fc to Spike proteins by ELISA. Error bars represent the standard deviation (SD), n = 3. Experiments were performed at least three times with similar results.