Figure EV3. Differential cell surface expression of PD‐L1, PD‐1, CD73 and TIM3 in IRS_high vs IRS_low tumor samples.

• A–D
  Flow cytometry determination of various cell surface markers (as indicated) within different tumor immune subsets or CD45‐ cells between the two groups of tumors (IRS_high vs IRS_low), according to the clustering depicted in Fig 1D. Box plots display group of numerical data through their 3^rd and 1^st quartiles (box), mean (central band), minimum and maximum (whiskers). In each bar graph, each dot represents one tumor. Statistical analyses: Wilcoxon rank‐sum test, ns. P > 0.05. Only data ≥ 500 events were plotted here. N/A: data not available or < 500 events.