Table 4. Percentages of urologic complications that developed post-transplant, as reported by other kidney transplant studies of extravesical ureteroneocystostomies, stratified by routine stent placement (Yes/No).
Study Description Placed | Median/Mean | Percentage Developing a Urologic Complication | |
Follow-up (mo) | Routine Stent Placed | No Routine Stent | |
1. Mangus-Haag (2004) Meta-analysis [1]: | |||
5 Randomized Trials Combined | 12a | 1.5% (6/407) | 9.0% (35/389) |
44 Cohort Studies Combined | variousa | 3.2% (137/4,245) | 4.8% (433/9,077) |
2. Randomized Trial, Osman et al (2005) [26]: | |||
Lich-Gregoir | 10.8 | 4.2% (2/48) | 0.0% (0/50) |
3. Randomized Trial, Ooms et al (2020) [25]: | |||
Lich-Gregoir | 12 | 8.0% (8/100) | 22.0% (22/100) |
4. Cohort Study, Secin et al (2002) [27]: | |||
Lich-Gregoir | 77 | --------------- | 13.0% (54/416) |
Shanfield “One-Stitch” | 24 | --------------- | 13.2% (21/159) |
5. Randomized Trial, Zargar et al (2005) [28]: | |||
Lich-Gregoir | 12 | 4.0% (4/100) | --------------- |
Taguchi “One-Stitch” | 8 | 9.1% (4/44) | --------------- |
6. Cohort Study, Veale et al (2007) [29]: | |||
Lich-Gregoir | 48 | --------------- | 3.9% (14/360) |
Shanfield “One-Stitch” | 48 | --------------- | 15.6% (55/353) |
7. Cohort Study, Pacovsky et al (2007) [30]: | |||
Lich-Gregoir | 30 | --------------- | 16.0% (4/25) |
Taguchi “One-Stitch” | 27 | --------------- | 18.2% (4/22) |
8. Cohort Study, Lee et al (2007) [31]: | |||
Lich-Gregoir | 33.4 | --------------- | 5.9% (14/238) |
Taguchi “One-Stitch” | 37.8 | --------------- | 15.1% (11/73) |
9. Cohort Study, Georgiev et al (2007) [32]: | |||
Lich-Gregoir | 12 | 5.9% (11/186) | 17.9% (29/162) |
10. Cohort Study, Tillou et al (2009) [33]: | |||
Lich-Gregoir | 12 | 5.3% (22/412) | --------------- |
11. Cohort Study, Ameer et al (2011) [34]: | |||
Lich-Gregoir | 34 | --------------- | 6.1% (10/163)b |
Taguchi “One-Stitch” | 44 | --------------- | 5.7% (12/209)b |
12. Cohort Study, Kayler et al (2012) [35]: | |||
Lich-Gregoir | >6 | 3.9% (12/307) | 4.6% (15/327)c |
13. Cohort Study, Whang et al (2020) [36–38]: | |||
Lich-Gregoir | >24 | 2.5% (95/3,856)d | --------------- |
aThe 12 months of follow-up shown for the 5 randomized trial results reported by Mangus and Haag1 was taken as the median follow-up among the 5 reported median follow-ups of the individual trials (as listed according to Mangus and Haag [1]): 3, 24, 24, 12, and 3 months post-transplant, respectively. Regarding the 44 cohort studies that were used in meta-analysis reported by Mangus and Haag [1], patient follow-up varied across the 44 different studies.
bPatients who developed a hematuria requiring intervention were not included as urologic complications here.
cA modified “full thickness” Lich-Gregior technique was used in the non-stented group.
dWhile UPJ obstruction and symptomatic vesicoureteral reflux were included as urologic complications in the Whang et al reports, yielding an overall incidence of 7.0% (269/3,856) for the occurrence of any urologic complication, these 2 types of complications were reported as occurring mostly late (beyond the first year) post-transplant. Thus, these 2 types of complications were excluded here.