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. 2021 Jan 11;16(1):e0244248. doi: 10.1371/journal.pone.0244248

Table 4. Percentages of urologic complications that developed post-transplant, as reported by other kidney transplant studies of extravesical ureteroneocystostomies, stratified by routine stent placement (Yes/No).

Study Description Placed Median/Mean Percentage Developing a Urologic Complication
Follow-up (mo) Routine Stent Placed No Routine Stent
1. Mangus-Haag (2004) Meta-analysis [1]:
    5 Randomized Trials Combined 12a 1.5% (6/407) 9.0% (35/389)
    44 Cohort Studies Combined variousa 3.2% (137/4,245) 4.8% (433/9,077)
2. Randomized Trial, Osman et al (2005) [26]:
    Lich-Gregoir 10.8 4.2% (2/48) 0.0% (0/50)
3. Randomized Trial, Ooms et al (2020) [25]:
    Lich-Gregoir 12 8.0% (8/100) 22.0% (22/100)
4. Cohort Study, Secin et al (2002) [27]:
    Lich-Gregoir 77 --------------- 13.0% (54/416)
    Shanfield “One-Stitch” 24 --------------- 13.2% (21/159)
5. Randomized Trial, Zargar et al (2005) [28]:
    Lich-Gregoir 12 4.0% (4/100) ---------------
    Taguchi “One-Stitch” 8 9.1% (4/44) ---------------
6. Cohort Study, Veale et al (2007) [29]:
    Lich-Gregoir 48 --------------- 3.9% (14/360)
    Shanfield “One-Stitch” 48 --------------- 15.6% (55/353)
7. Cohort Study, Pacovsky et al (2007) [30]:
    Lich-Gregoir 30 --------------- 16.0% (4/25)
    Taguchi “One-Stitch” 27 --------------- 18.2% (4/22)
8. Cohort Study, Lee et al (2007) [31]:
    Lich-Gregoir 33.4 --------------- 5.9% (14/238)
    Taguchi “One-Stitch” 37.8 --------------- 15.1% (11/73)
9. Cohort Study, Georgiev et al (2007) [32]:
    Lich-Gregoir 12 5.9% (11/186) 17.9% (29/162)
10. Cohort Study, Tillou et al (2009) [33]:
    Lich-Gregoir 12 5.3% (22/412) ---------------
11. Cohort Study, Ameer et al (2011) [34]:
    Lich-Gregoir 34 --------------- 6.1% (10/163)b
    Taguchi “One-Stitch” 44 --------------- 5.7% (12/209)b
12. Cohort Study, Kayler et al (2012) [35]:
    Lich-Gregoir >6 3.9% (12/307) 4.6% (15/327)c
13. Cohort Study, Whang et al (2020) [36–38]:
    Lich-Gregoir >24 2.5% (95/3,856)d ---------------

aThe 12 months of follow-up shown for the 5 randomized trial results reported by Mangus and Haag1 was taken as the median follow-up among the 5 reported median follow-ups of the individual trials (as listed according to Mangus and Haag [1]): 3, 24, 24, 12, and 3 months post-transplant, respectively. Regarding the 44 cohort studies that were used in meta-analysis reported by Mangus and Haag [1], patient follow-up varied across the 44 different studies.

bPatients who developed a hematuria requiring intervention were not included as urologic complications here.

cA modified “full thickness” Lich-Gregior technique was used in the non-stented group.

dWhile UPJ obstruction and symptomatic vesicoureteral reflux were included as urologic complications in the Whang et al reports, yielding an overall incidence of 7.0% (269/3,856) for the occurrence of any urologic complication, these 2 types of complications were reported as occurring mostly late (beyond the first year) post-transplant. Thus, these 2 types of complications were excluded here.