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. 2021 Jan 7;14:97–110. doi: 10.2147/OTT.S266186

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© 2021 Wu et al.

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Circ_0007444 inhibited proliferation, migration, invasion, and promoted apoptosis of OC cells. (A) qRT-PCR revealed that the expression of circ_0007444 in SKOV3 and OVCAR3 cells was successfully regulated by transfection. (B) According to CCK-8 assay, it could be noted that circ_0007444 prominently attenuated proliferation of OC cells. (C) Flow cytometry results indicated that circ_0007444 markedly enhanced OC cells apoptosis. (D) By wound healing assay, circ_0007444 obviously inhibited OC cells migration. (E) Transwell experiment illustrated that circ_0007444 remarkably suppressed the invasion ability of OC cells. Cells were stained by 0.1% crystal violet for 10 minutes. **P<0.01.