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. 2021 Jan 7;14:97–110. doi: 10.2147/OTT.S266186

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© 2021 Wu et al.

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Circ_0007444 inhibited OC growth in vivo. (A) Circ_0007444 decreased the xenograft tumor volume in nude mice. (B) The xenograft tumors in each mice were photographed. (C) Circ_0007444 diminished the xenograft tumor weight in nude mice. (D) According to immunohistochemistry, circ_0007444 decreased Ki67 expression and increased PTEN expression in xenograft tumors. Meanwhile, circ_0007444 facilitated the apoptosis in xenograft tumors based on the Tunel assay. **P<0.01.