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. 2020 Nov 9;62(1):90–99. doi: 10.4111/icu.20200119

Table 3. Summary of selected angiogenesis-related genes that decreased in the high-glucose (HG) group compared with the normal-glucose (NG) group.

Gene symbol Fold change Raw data (RC) KEGG input Transcript_id Description
HG/NG NG1 NG2 NG3 NG4 HG1 HG2 HG3 HG4 Entrez ID
Wnt7b 0.383 25 8 25 25 6 4 4 18 22422 NM_009528 Wingless-type MMTV integration site family, member 7B
Ctgf 0.432 26,261 28,683 26,265 26,262 12,606 12,690 12,153 15,186 14219 NM_010217 Connective tissue growth factor
Ramp1 0.523 191 108 191 191 124 72 93 88 51801 NM_016894 Receptor (calcitonin) activity modifying protein 1
Nox1 0.542 47 18 47 47 23 15 23 29 237038 NM_172203 NADPH oxidase 1
Cxcl12 0.545 732 691 730 731 380 446 410 523 20315 NM_013655 Chemokine (C-X-C motif) ligand 12
Hbegf 0.564 20,479 11,774 20,479 20,479 10,103 9,102 12,227 13,205 15200 NM_010415 Heparin-binding EGF-like growth factor
Adm2 0.565 1,074 1,139 1,074 1,074 620 666 713 791 223780 NM_182928 Adrenomedullin 2
Serpine1 0.581 88,771 67,443 88,771 88,771 50,387 52,935 52,574 56,240 18787 NM_008871 Serine (or cysteine) peptidase inhibitor, clade E, member 1
Cyr61 0.598 32,600 27,400 32,600 32,600 20,205 18,159 21,347 23,270 16007 NM_010516 Cysteine rich protein 61
Loxl2 0.607 27,739 17,667 27,738 27,733 14,919 14,002 18,232 19,561 94352 NM_033325 Lysyl oxidase-like 2
Sox18 0.630 31 24 31 31 17 23 15 24 20672 NM_009236 SRY (sex determining region Y)-box 18
Angptl4 0.637 29,720 26,036 29,720 29,720 18,692 20,439 20,586 21,674 57875 NM_020581 Angiopoietin-like 4
Thbs1 0.638 418,163 252,972 418,164 418,164 234,104 246,596 267,973 289,271 21825 NM_011580 Thrombospondin 1
Shb 0.647 850 619 850 850 472 425 659 713 230126 NM_001033306 Src homology 2 domain-containing transforming protein B
Arhgap22 0.651 3,455 2,224 3,455 3,455 2,080 1,759 2,470 2,624 239027 NM_153800 Rho GTPase activating protein 22
Pgf 0.657 978 531 978 979 384 529 712 860 18654 NM_008827 Placental growth factor