Table 6. Univariate and multivariate analyses of predictive factors for progression-free survival.
| Risk factor | Univariate analysis | p-value | Multivariate analysis | p-value | ||
|---|---|---|---|---|---|---|
| Hazard ratio | 95% confidence interval | Hazard ratio | 95% confidence interval | |||
| GPS (0, 1 vs. 2) | 4.99 | 1.69–14.75 | <0.01 | 4.56 | 1.52–13.73 | <0.01 |
| NLR, ≥4.1 | 3.17 | 0.89–11.26 | 0.07 | |||
| PI (0, 1 vs. 2) | 2.25 | 0.77–6.58 | 0.14 | |||
| PLR, ≥320 | 2.97 | 1.07–8.21 | 0.04 | 2.59 | 0.92–7.25 | 0.07 |
| PNI, <32 | 4.99 | 1.69–14.75 | <0.01 | NA | NA | NA |
| SII, ≥120×104/m3 | 2.49 | 0.79–7.85 | 0.12 | |||
| AGR, <1.1 | 2.54 | 0.89–7.24 | 0.08 | |||
GPS, Glasgow prognostic score; NLR, neutrophil-to-lymphocyte ratio; PI, prognostic index; PLR, platelet-to-lymphocyte ratio; PNI, prognostic nutritional index; SII, systemic immune-inflammation index; AGR, albumin-to-globulin ratio; NA, not available.