Fig. 3. Uncultured species are predominant among human gut phyla.
a, Maximum-likelihood phylogenetic tree of the 4,616 bacterial species detected in the human gut. Clades are colored by the cultured status of species, with outer circles depicting the GTDB phylum annotation. Bar graphs in the outermost layer indicate the number of genomes from each species. The order Comantemales ord. nov. is highlighted with dark green branches. b, Proportion of species within the 25 prokaryotic phyla detected according to cultured status. Numbers in parentheses represent the total number of species in the corresponding phylum. c, Phylogenetic tree of species belonging to the order Comantemales ord. nov. (phylum Firmicutes A), the largest phylogenetic group exclusively represented by uncultured species. The geographic distribution of each species and the number of genomes recovered are represented below the tree. The species previously classified as Candidatus ‘Borkfalki ceftriaxensis’ is indicated with an asterisk.