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LRIC treatment regulated circulating pro-inflammatory and anti-inflammatory factors. (A) pro-inflammatory cytokines CXCL1, TNFα, IL-1β, IFNγ,IL-5, and IL-6 levels in plasma. (B) anti-inflammatory cytokines IL-10, IL-13, and IL-4 levels in plasma. Data are expressed as mean ± SD, * P<0.05, * * P<0.01, * * * P<0.001, WKY-CON vs. SHR-CON, SHR-CON vs. SHR-RIC. N = 5 each group.
