Table 1.
Patient characteristics at baseline (n = 39)
| n | % | |
|---|---|---|
| Gender | ||
| Female | 22 | 56.4 |
| Male | 17 | 43.6 |
| Age (years) | ||
| Median (range) | 56 (28–65) | |
| 28–42 years | 5 | 12.8 |
| 43–65 years | 34 | 87.2 |
| Weight (kg), median (range) | 76.0 (42.9–115.0) | |
| Height (cm), median (range) | 169.0 (149.0–187.0) | |
| BSA (m2), median (range) | 1.9 (1.4–2.3) | |
| Heart rate (bpm), median (range) | 76 (56-103) | |
| Systolic blood pressure (mmHg), median (range) | 123 (93–147) | |
| Diastolic blood pressure (mmHg), median (range) | 74 (56–86) | |
| Body temperature (ºC), median (range) | 36.6 (35.0–37.3) | |
| ECOG PS | ||
| 0 | 17 | 43.6 |
| 1 | 22 | 56.4 |
| ECG | ||
| Normal | 29 | 74.4 |
| Non-significant abnormalities | 10 | 25.6 |
| LVEF, median (range) | ||
| ECHO (n = 35) | 62.0 (50.0–75.0) | |
| MUGA (n = 4) | 65.5 (56.0–67.0) | |
| Tumor type | ||
| Endometrial carcinoma | 9 | 23.1 |
| Head and neck carcinoma | 6 | 15.4 |
| Neuroendocrine tumors | 5 | 12.8 |
| Small cell lung cancer | 5 | 12.8 |
| Biliary tract carcinoma | 4 | 10.3 |
| Ewing’s family of tumors | 3 | 7.7 |
| Germ cell tumor | 3 | 7.7 |
| BRCA 1/2-associated metastatic breast carcinoma | 2 | 5.1 |
| Carcinoma of unknown primary site | 2 | 5.1 |
bpm beats per minute, BSA body surface area, ECG electrocardiogram, ECHO echocardiography, ECOG PS Eastern Cooperative Oncology group performance status, LVEF left-ventricular ejection fraction, MUGA multiple-gated acquisition scan