Table 3.
Parameter estimates for direct model and delayed effect model
| MVOF | Final direct model | Final delayed effect model | ||
|---|---|---|---|---|
| 2550 | 2459 | |||
| Parameter | Estimate | RSE (%) | Estimate | RSE (%) |
| Intercept, ms | − 1.47 | 8.18 | − 3.95 | 7.22 |
| Slope, ms L/µg | 0.072 | 12.2 | 0.289 | 17.6 |
| Keo, 1/h | – | 0.298 | 0.292 | |
| Residual variability (%) | 9.25 | 3.83 | 8.36 | 3.92 |
| Variability in intercept (%) | 165 | 13.1 | 105 | 13.3 |
| Variability in slope (%) | 14.0 | 73.9 | 29.8 | 40.3 |
| Correlation intercept-slope (%) | − 49.5 | 29.4 | − 63.5 | 25.8 |
Keo, equilibration rate constant; MVOF minimum value of the objective function; RSE relative standard error