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. 2021 Jan 11;6:10. doi: 10.1038/s41392-020-00437-8

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© The Author(s) 2020

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 1 — Chromatin-modifying genes were frequently mutated in diffuse large B-cell lymphoma (DLBCL). a Gene mutations identified by whole-genome/exome sequencing (WGS/WES) in the training cohort of 316 patients (upper panel) and by targeted sequencing in the validation of 303 patients (lower panel) with DLBCL. b Type and a number of non-silent somatic mutations (upper panel), and the number of non-silent somatic single-nucleotide variants (SNVs) identified by WGS/WES/targeted sequencing (lower panel) in the training and validation cohorts of 619 DLBCL patients. c Circos diagram of the correlation between genes, representing the combinations of mutations in different genes