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. 2021 Jan 11;11:322. doi: 10.1038/s41598-020-79121-4

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© The Author(s) 2021

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Predictive potential of intermediate monocyte percentage in CLL patients. (A) ROC curve for treatment-naïve patients sampled at the diagnosis, subdivided according to the treatment requirement during the post-sampling follow-up. K–M curves show time-to-treatment (B) in groups of newly diagnosed treatment-naïve (TN) CLL patients and (C) validation cohort of CLL patients in all stages of the disease. The green curves show patients with a low percentage of intermediate MON, while the red curves show patients with more than 5.4% of intermediate MON.