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. 2021 Jan 11;11:423. doi: 10.1038/s41598-020-80218-z

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© The Author(s) 2021

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Serum cortisol concentrations one week after ear occlusion (a) and proposed mechanisms of hippocampal neurogenesis impairment following CHL (b). (a) Concentrations of serum cortisol were significantly higher in the bCHL group compared to that in the nCHL group. There were no significant differences between the nCHL and uCHL groups or the uCHL and bCHL groups (n = 5 per each group). ***p < 0.001. DG, dentate gyrus.