Table 4.
The adjusted risks for rapid eGFR decline (eGFR decline > 3 ml/min/1.73 m2/year) within 1 year prior to questionnaire examination in study patients stratified by age according to self-care behavior and disease knowledge scores.
| Age ≥ median (67 years) | Age < median (67 years) | |||||
|---|---|---|---|---|---|---|
| Percentage of eGFR decline > 3 ml/min/1.73 m2/year | Rapid eGFR decline | Percentage of eGFR decline > 3 ml/min/1.73 m2/year | Rapid eGFR decline | |||
| Adjusted odds ratio (95% Cl) | p-value | Adjusted odds ratio (95% Cl) | p-value | |||
| Self-care behavior (per score) | 67/227 (29.5) | 0.97 (0.94–1.00) | 0.07 | 80/227 (35.2) | 0.97 (0.94–0.99) | 0.02 |
| Self-care behavior (quartiles) | ||||||
| Quartile 1 | 20/51 (39.2) | Reference | 33/74 (44.6) | Reference | ||
| Quartile 2 | 14/45 (31.1) | 0.65 (0.27–1.55) | 0.3 | 23/62 (37.1) | 0.80 (0.39–1.66) | 0.6 |
| Quartile 3 | 22/76 (28.9) | 0.66 (0.30–1.44) | 0.3 | 13/50 (26.0) | 0.48 (0.21–1.09) | 0.07 |
| Quartile 4 | 11/55 (20.0) | 0.39 (0.16–0.93) | 0.03 | 11/41 (26.8) | 0.42 (0.17–1.00) | 0.05 |
| Disease knowledge (per score) | 67/227 (29.5) | 0.96 (0.90–1.01) | 0.1 | 80/227 (35.2) | 0.86 (0.81–0.92) | < 0.001 |
| Disease knowledge (quartiles) | ||||||
| Quartile 1 | 34/93 (36.6) | Reference | 25/45 (55.6) | Reference | ||
| Quartile 2 | 10/43 (23.3) | 0.59 (0.25–1.36) | 0.2 | 22/47 (46.8) | 0.91 (0.37–2.22) | 0.8 |
| Quartile 3 | 15/56 (26.8) | 0.69 (0.32–1.49) | 0.4 | 18/64 (28.1) | 0.30 (0.13–0.70) | 0.006 |
| Quartile 4 | 8/35 (22.9) | 0.61 (0.24–1.55) | 0.3 | 15/71 (21.1) | 0.19 (0.08–0.46) | < 0.001 |
| Interaction between self-care score and disease knowledge score | 67/227 (29.5) | 0.99 (0.99–1.00) | 0.04 | 80/227 (35.2) | 0.99 (0.99–0.99) | < 0.001 |
| Low self-care score and low disease knowledge score | 24/67 (35.8) | Reference | 34/66 (51.5) | Reference | ||
| High self-care score and low disease knowledge score | 20/69 (29.0) | 0.78 (0.37–1.64) | 0.5 | 13/26 (50.0) | 1.09 (0.41–2.86) | 0.8 |
| Low self-care score and high disease knowledge score | 10/29 (34.5) | 1.07 (0.41–2.80) | 0.9 | 22/70 (31.4) | 0.37 (0.17–0.78) | 0.009 |
| High self-care score and high disease knowledge score | 13/62 (21.0) | 0.55 (0.24–1.23) | 0.1 | 11/65 (16.9) | 0.16 (0.07–0.39) | < 0.001 |
Adjusted model of self-care behavior and disease knowledge in rapid eGFR decline included age, sex and all variables in Table 1 whose p-value were < 0.05 including diabetes mellitus, hemoglobin, baseline estimated glomerular filtration rate, and log-formed urine protein-creatinine ratio in unadjusted model.
Self-care score quartile cut at 59, 67 and 72.
Disease knowledge score quartile cut at 18, 22 and 25.
Low self-care as less than median of self-care score; high self-care as above median of self-care score.
Low disease knowledge as less than median of disease knowledge score; High disease knowledge as above median of disease knowledge score.