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. 2021 Jan 11;11:449. doi: 10.1038/s41598-020-80049-y

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© The Author(s) 2021

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Correlations of the 5S and 45S rDNA copy numbers in 1000 Genomes Project data. (a) Correlation of the 18S to the 5S in the high-coverage 1000 Genomes Project data (n = 2419). (b) Correlation of the 18S to the 5S in the subset of 1000 Genomes Project data samples also analyzed in the low-coverage dataset (n = 163). (c) Correlation of the 18S to the 5S in the low-coverage 1000 Genomes Project data (n = 163). (d,e) Comparison of rDNA copy number estimates for the same cell lines sequenced separately in the high-coverage and low-coverage 1000 Genomes datasets for the 18S locus (d) and the 5S locus (e). Spearman’s rho is indicated in each panel, n = 163.