Table 4.
Comparison of the false positive rate, biopsy rate, and sensitivity between the radiologist’s BI-RADS assessment and the proposed nomogram.
| False positive rate | Biopsy rate | Sensitivity | ||||
|---|---|---|---|---|---|---|
| Development cohort | Validation cohort | Development cohort | Validation cohort | Development cohort | Validation cohort | |
|
Radiologist’s BI-RADS ≥ 4A |
68 (62, 73) [173/256] |
97 (95, 99) [151/155] |
72 (67, 77) [215/299] |
98 (96, 100) [160/164] |
98 (88, 100) [42/43] |
100 (66, 100) [9/9] |
| Nomogram ≥ 114 |
31 (26, 37) [80/256] |
45 (37, 52) [69/155] |
41 (35, 46) [121/299] |
48 (40, 55) [78/164] |
95 (84, 99) [41/43] |
100 (66, 100) [9/9] |
| P value | < .001 | < .001 | < .001 | < .001 | .317 | NA |
Data in parentheses are the 95% confidence intervals, and the data in brackets are the numerators/denominators.
BI-RADS, Breast Imaging Reporting and Data System.