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. 2021 Jan 11;11:316. doi: 10.1038/s41598-020-79604-4

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© The Author(s) 2021

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Body weight and fat mass between chow-exposed and HFD-exposed rat offspring at different ages. (A) Body weights of male chow-exposed and HFD-exposed rat offspring of various ages. (B) Body weights of female chow-exposed and HFD-exposed rat offspring of various ages. (C) Fat mass of subcutaneous adipose tissue (SAT) in male and female offspring. (D) Fat mass of visceral adipose tissue (VAT) in male and female offspring. (E) % adiposity (fat/body weight) of SAT in male and female offspring. (F) % adiposity of VAT in male and female offspring. (G) T1-weighted magnetic resonance (MR) images in 3-week-old chow-exposed and HFD-exposed male rat offspring. (H) T1-weighted MR images in 8-week-old chow-exposed and HFD-exposed male rat offspring. For (A–F), values are expressed as means ± SEs, n = 6 for each group. **p < 0.01, *p < 0.05, compared to the corresponding control. For E and F, the images above were obtained in the coronal plane; the images below were obtained in the transverse section. The arrows indicate fat distribution in subcutaneous and visceral adipose tissues.