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. 2021 Jan 11;11:393. doi: 10.1038/s41598-020-79803-z

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© The Author(s) 2021

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Antibody mediated inhibition of ZIKV-T infection of A549 cells. A549 cells were pre-treated with no antibody as a control or with anti-GRP78 N- and C-terminus antibodies at varying concentrations, or with 20 µg of a rabbit polyclonal anti-phospho-PERK antibody as a non-relevant antibody followed by ZIKV-T infection at MOI 5. At 18 h p.i., (A) the cells were collect to determine the percentage of cell infection by flow cytometry and (B) the culture supernatant was collected to determine viral titer by standard plaque assay. The graphs are representative of three independent biological replicates with duplicate plaque assay. Error bars represent SEM. (*p value < 0.05).