Table 2.
Association between annual renal function decline (%) and cytokines
| Variable | Unadjusted |
Adjusteda |
||
|---|---|---|---|---|
| r | P value | r | P value | |
| A-FABP, µg/L | –0.055 | 0.24 | –0.150 | 0.005 |
| hs-CRP, mg/dL | –0.013 | 0.78 | 0.001 | 0.99 |
| Fibrinogen, mg/dL | –0.064 | 0.23 | –0.046 | 0.39 |
| Total adiponectin, µg/mL | –0.023 | 0.63 | 0.071 | 0.19 |
| HMW adiponectin, µg/mL | –0.039 | 0.40 | 0.055 | 0.31 |
| Interleukin-6, pg/mL | –0.043 | 0.36 | 0.051 | 0.35 |
| TNF-α, pg/mL | 0.037 | 0.43 | –0.045 | 0.40 |
| PTX3, ng/mL | –0.042 | 0.37 | –0.070 | 0.19 |
A-FABP, adipocyte fatty acid-binding protein; hs-CRP, high-sensitivity C-reactive protein; HMW, high molecular weight adiponectin; TNF-α, tumor necrosis factor-α; PTX3, pentraxin-3.
a
Partial Spearman’s correlation coefficients (r) are presented after adjustment for age, sex, body mass index, glycosylated hemoglobin, and baseline estimated glomerular filtration rate.