Figure 1. Study Workflow.
Participants are enrolled in the research study, and samples collected at the collection sites are sent weekly via preferred courier to Newborn Screening Ontario (NSO), Ontario, Canada for analysis. Reporting procedures from the NSO to the collection site include provision of reports on sample quality, on newborns’ risk of congenital hypothyroidism (CH), medium-chain acyl-CoA dehydrogenase deficiency (MCADD) and haemoglobinopathies (HGBs) and quarterly reports summarizing study progress. Adapted from 12 under a CC BY 4.0 license.
ANC, antenatal care; DBS, dried blood spot; NSO, Newborn Screening Ontario; CH, congenital hypothyroidism; HGB, hemoglobinopathies; MCADD, medium-chain acyl-CoA dehydrogenase deficiency.