. 2021 Jan 5;12:683–693. doi: 10.2147/JEP.S289478

Table 2.

Packed Cell Volume, Rectal Temperature and Body Weight of Infected Mice Treated with 80% Methanol Extract of the Stem Bark of F. angolensis In the 4-Day Suppressive Test

Groups	Packed Cell Volume			Rectal Temperature			Body Weight
Groups	D₀	D₄	% Change	D₀	D₄	% Change	D₀	D₄	% Change
2% TW80	60.82±1.17	57.36±1.02	−6.03	36.86±0.16	34.73±0.16	−6.13	28.27±0.21	26.85±0.22	−5.29
CQ25 mg/kg	60.76±1.33	60.53±1.14	−0.38^a***	36.54±0.25	36.23±0.39	−0.86 ^a***	28.84±0.32	28.34±0.29	−1.76 ^a***
200 mg/kg	60.55±0.57	57.96±0.48	−4.47 ^a*be*	36.52±0.13	35.48±0.18	−2.93 ^a*be	28.75±0.32	27.75±0.34	−3.60 ^b***
400 mg/kg	60.80±0.69	58.33±0.54	−3.45 ^a*be	36.40±0.22	35.52±0.19	−2.48 ^a*b*	28.81±0.44	27.96±0.35	−3.04^ab*
600 mg/kg	60.91±0.45	59.99±0.52	−1.53 ^a*b*	36.25±0.18	35.62±0.20	−1.77 ^a*b*	28.42±0.54	27.64±0.66	−2.82^ab*

Notes: Values are expressed as mean ± SEM; n = 6; ^aAgainst negative control; ^bAgainst CQ25 mg/kg; ^cAgainst 200 mg/kg; ^dAgainst 400 mg/kg; ^eAgainst 600 mg/kg; *p<0.05; **p<0.01; ***p<0.001.

Abbreviations: 2% TW80, 2% Tween80; CQ, chloroquine; D₀, pre-treatment value on day 0; D₄, post-treatment value on day 4.