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. 2021 Jan 5;12:683–693. doi: 10.2147/JEP.S289478

Table 3.

Parasitemia and Survival Time of Infected Mice Treated with Solvent Fractions of the Stem Bark of F. angolensis in the 4-Day Suppressive Test

Groups % Parasitemia % Suppression Survival Time (Days)
2% TW80 37.78±0.64 7.45±0.22
CQ25 mg/kg 0.00±0.00 100.00a*** 28.00±0.00a***
200 mg/kg CF 25.62±0.44 32.19 a***b***d**e** 10.15±0.25a***b***e*
400 mg/kg CF 23.76±0.35 37.11 a***b*** 11.33±0.39a***b***
600 mg/kg CF 22.48±0.21 40.50 a***b*** 12.02±0.27a***b***
2% TW80 37.92±0.65 7.18±.017
CQ25 mg/kg 0.00±0.00 100.00a*** 28.00±0.00a***
200 mg/kg BF 21.35±0.38 43.70 a***b***d**e*** 11.85±0.39a***b***d**e*
400 mg/kg BF 19.66±0.34 48.15 a***b*** 12.88±0.23a***b***e*
600 mg/kg BF 17.85±0.36 52.93 a***b*** 14.78±0.26a***b***
2% TW80 37.85±0.42 7.17±0.23
CQ25 mg/kg 0.00±0.00 100.00a*** 28.00±0.00a***
200 mg/kg AF 33.56±0.38 11.33 a***b***e* 8.67±0.24a***b***e*
400 mg/kg AF 31.44±0.27 16.94 a***b*** 9.14±0.26a***b***
600 mg/kg AF 30.45±0.23 19.55 a***b*** 9.45±0.22a***b***

Notes: Values are expressed as mean ± SEM; n = 6; aAgainst negative control; bAgainst CQ25 mg/kg; cAgainst 200 mg/kg; dAgainst 400 mg/kg; eAgainst 600 mg/kg; *p<0.05; **p<0.01; ***p<0.001.

Abbreviations: CF, chloroform fraction; BF, butanol fraction; AF, aqueous fraction; 2% TW80, 2% Tween80; CQ, chloroquine.