. 2021 Jan 5;12:683–693. doi: 10.2147/JEP.S289478

Table 6.

Packed Cell Volume, Rectal Temperature and Body Weight of Infected Mice Treated with n-Butanol Fraction of the Stem Bark of F. angolensis in Rane’s Test

Groups	Packed Cell Volume			Rectal Temperature			Body Weight
Groups	D₃	D₇	% Change	D₃	D₇	% Change	D₃	D₇	% Change
2% TW80	50.96±0.65	42.85±0.42	−18.93	35.23±0.24	33.38±0.25	−5.54	27.99±0.45	25.65±0.52	−9.12
CQ25 mg/kg	51.66±0.45	52.34±0.25	−1.30 ^a***	35.15±0.21	35.35±0.19	−0.57^a***	28.49±0.52	28.96±0.43	−1.62^a***
200 mg/kg	51.08±0.28	47.11±0.18	−8.43^{a*bde**}	35.28±0.15	33.88±0.20	−4.13 ^{a*bde***}	27.86±0.33	25.77±0.25	−8.11^ab**
400 mg/kg	50.89±0.71	48.16±0.22	−5.67 ^a*b*	35.26±0.35	34.12±0.34	−3.34 ^a*b*	28.08±0.43	26.12±0.42	−7.50^ab*
600 mg/kg	51.58±0.11	49.36±0.17	−4.50 ^a*b*	35.23±0.19	34.46±0.22	−2.23 ^a*b*	28.19±0.53	26.35±0.32	−6.98^a*b*

Notes: Values are expressed as mean ± SEM; n = 6; ^aCompared with negative control; ^bTo CQ25 mg/kg; ^cTo 200 mg/kg; ^dTo 400 mg/kg; ^eTo 600 mg/kg; *p<0.05; **p<0.01; ***p<0.001.

Abbreviations: 2% TW80, 2% Tween80; CQ, chloroquine; D₃, pre-treatment value on day 3; D₇, post-treatment value on day 7.