Table 3.
Association between acute kidney injury and in-hospital mortality
| Variables | Univariate analysis |
Multivariate analysis |
||||
|---|---|---|---|---|---|---|
| odds ratio | 95% CI | p value | odds ratio | 95% CI | p value | |
| Age | 1.032 | 1.012–1.053 | 0.002 | 1.029 | 0.999–1.061 | 0.056 |
| Sex (female) | 0.623 | 0.384–1.009 | 0.055 | 0.454 | 0.217–0.950 | 0.036 |
| Comorbidities | ||||||
| Hypertension | 0.816 | 0.507–1.313 | 0.403 | |||
| Diabetes | 1.086 | 0.616–1.913 | 0.776 | |||
| Coronary artery disease | 2.256 | 1.058–4.810 | 0.035 | |||
| Chronic obstructive lung disease | 0.677 | 0.337–1.362 | 0.274 | 2.002 | 0.632–6.343 | 0.238 |
| Chronic kidney disease | 4.367 | 1.216–15.687 | 0.024 | 0.340 | 0.070–1.656 | 0.182 |
| NLR | 1.065 | 1.039–1.092 | <0.001 | 1.052 | 1.020–1.086 | 0.001 |
| Albumin | 0.812 | 0.760–0.869 | <0.001 | 0.886 | 0.820–0.958 | 0.002 |
| AKI | ||||||
| Non-AKI | Reference | Reference | ||||
| Stage 1 | 7.342 | 3.504–15.383 | <0.001 | 5.374 | 2.147–13.452 | <0.001 |
| Stage 2 | 7.495 | 3.130–17.946 | <0.001 | 6.216 | 2.011–19.210 | 0.002 |
| Stage 3 | 44.970 | 15.165–133.354 | <0.001 | 34.033 | 9.723–119.129 | <0.001 |
| SOFA score | 1.273 | 1.153–1.406 | <0.001 | 1.361 | 1.164–1.591 | <0.001 |
Variables included in multivariate analysis were age, sex, chronic obstructive lung disease, chronic kidney disease, NLR, albumin, AKI, and SOFA score. NLR, neutrophil-to-lymphocyte ratio; AKI, acute kidney injury; SOFA, Sepsis-Related Organ Failure Assessment.