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. Author manuscript; available in PMC: 2021 Jan 12.
Published in final edited form as: J Am Coll Cardiol. 2018 Sep 25;72(13):1555–1557. doi: 10.1016/j.jacc.2018.07.028

FIGURE 1. Histopathological Assessment of Cardiac Fibrosis and Myocellular Injury.

FIGURE 1

(A) Collagen volume fraction (CVF) (left y-axis) and modified Billingham Score for myocardial injury (right y-axis) of WKY rats treated with saline (solid blue bars) or DOX (solid orange bars) and SHRs treated with saline (hash-marked blue bars) or DOX (hash-marked orange bars). All values are mean ± SEM. (B) Representative microphotographs (20×) of left ventricles from each treatment group stained with Picrosirius red that identifies collagen. DOX = doxorubicin; SHR= spontaneously hypertensive; WKY = Wistar Kyoto.