Table 3.
HR (95% CI) for risk of myocardial infarction according to number of visits with a high TyG index
| Variables | Number of visits with a high TyG index* | ||||
|---|---|---|---|---|---|
| 0 | 1 | 2 | 3 | P for trend | |
| Case, n (%) | 173 (0.70) | 139 (1.40) | 126 (1.40) | 164 (1.68) | |
| Incidence rate, per 1000 person-y | 0.65 (0.56–0.75) | 1.07 (0.91–1.27) | 1.29 (1.09–1.54) | 1.55 (1.33–1.81) | |
| Model 1 | Reference | 1.69 (1.36–2.12) | 2.10 (1.67–2.64) | 2.52 (2.03–3.12) | < 0.0001 |
| Model 2 | Reference | 1.61 (1.28–2.01) | 1.90 (1.50–2.40) | 2.21 (1.77–2.76) | < 0.0001 |
| Model 3 | Reference | 1.54 (1.23–1.93) | 1.78 (1.41–2.26) | 2.04 (1.63–2.56) | < 0.0001 |
| Sensitivity analysis | Reference | 1.48 (1.16–1.91) | 1.78 (1.37–2.31) | 2.16 (1.69–2.78) | < 0.0001 |
CI confidence interval, HR hazard ratio, TyG triglyceride glucose
*High TyG index was defined as TyG index ≥ 8.83
Model 1, adjusted for age and sex at baseline
Model 2, adjusted for variables in model 1 plus level of education, income, smoking, alcohol abuse, physical activity, and BMI at baseline
Model 3, adjusted for variables in model 2 plus SBP, DBP, a history of hypertension, diabetes mellitus, and dyslipidemia, antidiabetic drugs, lipid-lowering drugs, antihypertensive drugs, HDL-C, LDL-C, and hs-CRP at baseline
Sensitivity analysis was adjusted for variables in model 3 and further excluded all deaths during the follow-up visits