Table 2.
Ultrasonic soft markers and conventional karyotyping
| Groups | Number of fetuses | Rate of chromosomal abnormalities (%) | Trisomy 21 | Trisomy 18 | Trisomy 13 | 47,XXY | 45,X | Mosaic chromosomal number abnormalities | Chromosomal structural abnormalities |
|---|---|---|---|---|---|---|---|---|---|
| Single ultrasonic soft marker | 729 | 26 (3.6) | 12 | 3 | 3 | 1 | 2 | 5 | |
| Short femur | 26 | 2 (7.7%) | 2 | ||||||
| Thickened nuchal translucency | 302 | 18 (6.0%) | 10 | 1 | 3 | 1 | 3 | ||
| Choroid plexus cyst | 54 | 2 (3.7%) | 2 | ||||||
| Absent nasal bone | 76 | 2 (2.6%) | 1 | 1 | |||||
| Ventriculomegaly | 115 | 2 (1.7%) | 1 | 1 | |||||
| Two ultrasonic soft markers | 322 | 13 (4.0%) | 7 | 1 | 1 | 1 | 3 | ||
| Three or more ultrasonic soft markers | 80 | 7 (8.8%) | 4 | 1 | 1 | 1 |