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Fucoidan induces apoptosis in A549 and H1650 NSCLC cells. a. Annexin V-PE/7-AAD double-staining and flow cytometry revealed that fucoidan effectively induced apoptosis in A549 and H1650 cells. LL (low left), LR (low right), UR (upper right), and UL (upper left) denote viable (live), early apoptotic, late apoptotic and necrotic cells, respectively. b. Western blot analysis of Bcl-2 and Bax expression and the Bax/Bcl-2 ratio in cells treated with fucoidan or untreated. ** P < 0.01
