Table 2.
The published functions of miR-365-3p and its validated targets
| Target genes | Genes name | Functions | References PMID |
|---|---|---|---|
| HDAC4 | Histone deacetylase 4 | Stimulate chondrocyte differentiation in chicken or mouse/osteoarthritis development in human | 21856783 |
| HDAC4 | Histone deacetylase 4 | Osteoarthiritis development in human | 27023516 |
| TTF1 | Thyroid transcription factor1 | Regulate lung cancer | 22185756 and 26337230 |
| CycD1/Bcl2 | Cyclin D1/Bcl apoptosis regulator 2 | Regulate colon cancer | 22072615 |
| SHC1 | Src homology domain containing 1 | Gemcitabine Regulate pancreatic cancer | 24216611 |
| NFIB | Nuclear factor I/B | Promote cutaneous squamous cell carcinoma | 24949940 |
| CycD1/cdc25A | Cyclin D1 | Contribute to gastric tumorigenesis | 24149576 |
| CycD1 | Cyclin D1 | Inhibit vascular smooth muscle cell proliferation | 24819721 and 24936138 |
| Pax6 | Paired box 6 | Regulate human retinoblastoma cells | 23660406 |
| Not clearly | Transport-related stress in turkeys | 26760121 | |
| Kcnh2 | Potassium voltage-gated channel subfamily H member 2 | Regulate nociceptive behaviors | 26937014 |
| IL-6 | Interleukin-6 | Host defense | 21518763 |
| Bcl-2 | Bcl apoptosis regulator 2 | Response low-density lipoprotein stimulation | 21640710 |