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. 2021 Jan 8;218(3):e20200839. doi: 10.1084/jem.20200839

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© 2021 Deuse et al.

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Figure 6. — Mechanistic interaction of CD47 with NK cell SIRPα. (A–E) B2M⁻^/⁻CIITA⁻^/⁻ CD47 tg hiECs engaged with primary NK cells (A) or NK cells from a cell line (B–E) using in vitro impedance assays in the presence or absence of a specific blocking antibody against CD47 (clone B6.H12) or a blocking peptide against SIRPα. Graphs show mean ± SD and three independent replicates per group and time point; three different E:T ratios are shown.