Genus-level microbial composition of non-SANC, persistent SANC, and intermittent SANC nostrils. (A) Relative abundance of genera detected by 16S amplicon sequencing of nostril swabs collected from 34 noncarrier nostrils, 22 intermittent (11 S. aureus-positive/11 S. aureus-negative) SANC nostrils, and 9 persistent SANC nostrils. (B) Shannon Index (alpha diversity) for noncarriers (NC), intermittent carriers (Int), and persistent carriers (P), calculated from the OTU data for each sample. (C) Bacterial density of each swab, grouped according to SANC status as in panel B. Panels B and C show individual values as well as box and whisker representation of the median, 25th and 75th percentiles (boxes), and minimum/maximum values (whiskers). P values were calculated using the Wilcoxin rank-sum test (panel B) and ordinary one-way ANOVA (panel C).