Table 2.
Lipid Biomarkers† | ||||||
---|---|---|---|---|---|---|
Total cholesterol (mmol/L) | LDL-C (mmol/L) |
HDL-C (mmol/L) |
Triglycerides (mmol/L) |
Apolipoprotein-AI (mg/dL) | Apolipoprotein-B (mg/dL) | |
CETP rs3764261 (C>A) | ||||||
CC (n = 126) | 4.87 (4.37–5.34) | 2.71 (0.74) | 1.26 (1.06–1.55) | 1.98 (1.22–2.44) | 157.6 (24.2) | 90.1 (79.3–106.0) |
CA (n = 140) | 4.90 (4.45–5.31) | 2.74 (0.87) | 1.40 (1.19–1.70) | 1.52 (1.11–2.03) | 164.3 (27.2) | 86.7 (76.5–102.0) |
AA (n = 33) | 5.10 (4.75–5.53) | 3.02 (0.61) | 1.53 (1.39–1.88) | 1.40 (1.13–1.78) | 171.7 (25.6) | 86.0 (77.6–99.5) |
p-value | 0.180 | 0.118 | <0.001 | 0.004 | 0.010 | 0.597 |
CETP rs708272 (G>A) | ||||||
GG (n = 101) | 4.84 (4.39–5.31) | 2.72 (0.78) | 1.32 (1.11–1.57) | 1.79 (1.18–2.27) | 158.6 (25.7) | 86.4 (78.2–99.8) |
GA (n = 153) | 4.95 (4.43–5.54) | 2.77 (0.83) | 1.35 (1.10–1.66) | 1.73 (1.16–2.44) | 161.6 (26.6) | 88.6 (78.0–108.5) |
AA (n = 45) | 4.92 (4.51–5.21) | 2.79 (0.72) | 1.50 (1.30–1.77) | 1.32 (1.05–1.53) | 173.0 (23.2) | 87.7 (76.5–94.6) |
p-value | 0.617 | 0.852 | 0.006 | 0.001 | 0.008 | 0.398 |
CETP rs12149545 (G>A) | ||||||
GG (n = 193) | 4.95 (4.43–5.37) | 2.77 (0.77) | 1.35 (1.14–1.61) | 1.66 (1.16–2.28) | 161.7 (25.6) | 88.9 (78.8–101.0) |
GA (n = 97) | 4.84 (4.42–5.34) | 2.74 (0.86) | 1.37 (1.17–1.72) | 1.58 (1.13–2.27) | 162.3 (27.0) | 87.1 (75.9–107.0) |
AA (n = 9) | 4.95 (4.60–5.44) | 2.69 (0.65) | 1.71 (1.27–1.98) | 1.37 (1.09–1.85) | 175.3 (27.2) | 84.2 (75.1–98.9) |
p-value | 0.756 | 0.937 | 0.119 | 0.516 | 0.312 | 0.666 |
Notes: †The parametric variables are given as mean (standard deviation) and the nonparametric variables are given as median (interquartile range). All biochemical measures are given in Système International units; conversions to conventional units are as follows: cholesterol (mg/dL), multiply by 38.6; triglycerides (mg/dL), multiply by 88.5.
Abbreviations: LDL-C, low-density lipoprotein cholesterol; HDL-C, high-density lipoprotein cholesterol.